 |
| [11] Publication Number: |
2146144 |
| [13] Kind of Document: |
C1 |
| [14] Publication Date: |
2000.03.10 |
| [19] Publishing Country or Organization: |
RU |
| [21] Appl. No.: |
97102060/14 |
| [22] Filled: |
1997.02.11 |
| [24] Effective Dates for Priority rights: |
1997.02.11 |
| [46] Claim(s) date: |
2000.03.10 |
| [51] Int. Cl.: |
A61K31/675, A61K31/40 |
| [71] Applicant: |
Vorozhtsov G.N., Kogan E.A., Loshchenov V.B., Luk'janets E.A., Meerovich G.A., Torshina N.L., Juzhakova O.A. |
| [75] Inventors: |
Vorozhtsov G.N., Kogan E.A., Loshchenov V.B., Luk'janets E.A., Meerovich G.A., Torshina N.L., Juzhakova O.A. |
| [73] Assignee: |
Vorozhtsov G.N., Kogan E.A., Loshchenov V.B., Luk'janets E.A., Meerovich G.A., Torshina N.L., Juzhakova O.A. |
[57] Abstract:
|
FIELD: medicine, oncology. SUBSTANCE:
invention relates to preparations used for photodynamic therapy
of patients with malignant neoplasms. Preparation for photodynamic
therapy is phosphinemethyl derivatives of phthalocyanine of the
general formula:PcM[CH2PO(OR)2]n where M is AlX, Zn, SnX2, SiX2,
TiO; X is OH, OP(O)R(OR), Br or other halogen; R is H, C2H5 or other
alkyl; n > 4 for Zn; n>=2 for tri- and tetravalent metals.
Preparation exerts the greater deep effect on tissues. EFFECT: enhanced
effectiveness of preparation as compared with known ones. 16 ex
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